Carotid Intima Media Thickness as a Cardiovascular Risk Factor
CIMT is a painless, noninvasive test that takes about 10-15 minutes to perform. CIMT uses ultrasound (so there is no radiation) and does not require the patient to disrobe.
CIMT is recommended by both the American Heart Association and the American College of Cardiology. As many as 50-60% of those who die from heart attacks or strokes have no previous signs or symptoms. These patients may have been classified as low or intermediate risk based on traditional risk factors. CIMT is more accurate in predicting disease than any other risk factor alone. CIMT significantly improves the assessment of cardiovascular risk in an individual by directly looking at the blood vessels. CIMT will catch more people with disease who were felt to be normal on stress tests. Stress tests only become positive when a patient generally has 70% or greater blockage of a coronary artery. We certainly want to know if we are at risk long before we have a blood vessel that is more than 70% blocked!
As part of our ongoing commitment to provide the latest advancements in preventive medicine, Cenegenics® is now offering an additional, state of the art, screening tool for vascular disease called CIMT. CIMT stands for Carotid Intima Media Thickness and refers to the combined thickness of the inner two layers (intima and media) of the carotid artery, which lies in the neck. The measurement of the thickness of the intima and media layers of the common carotid artery is highly predictive of future events (i.e. heart attack, stroke, sudden cardiac death).
Just the Facts for Men | The goals of the Cenegenics® program are to keep our patients at the lowest possible risk for the various diseases associated with aging and to improve their quality of life. This is accomplished through early detection, identification of risk factors, and proactive strategies designed to prevent disease as much as possible, rather than treating it once it is established.
See the Cardio Health System device’s page on our site for more information on the specific method/device we will be using to measure CIMT.
The test will be included in the initial Executive Health Evaluation.
Cenegenics® uses the Panasonic Cardio Health Station to measure carotid intima media thickness as a cardiovascular risk factor as part of the CIMT exam.
The Cardio health station is FDA cleared, in-office ultrasound imaging that helps you directly identify atherosclerotic cardiovascular disease (ASCVD) allowing you to make a more informed decision about your patients’ treatment options.
The Physicians' Challenge
Assessment of cardiovascular risk in asymptomatic patients with cardiovascular disease is one of the leading causes of death globally. To assess risk, doctors typically review traditional risk factors, such as total cholesterol, blood pressure, smoking history, age, gender, lipid profile (HDL/LDL levels), and family history. However, these conventional tests can be poor predictors of future atherothrombotic events. Relying on these factors may result in misclassification of risk. In a major study of 136,905 patients hospitalized with coronary artery disease, only 23% had high LDL levels* (above 130 mg/dl) and would be identified by traditional risk factors. Yet, in a large outcome study of 10,000 asymptomatic subjects with a 10 year follow-up (mean age = 53), ultrasound identified 98.6% of future atherothrombotic events.**
*Sachdeva et al. AHJ, Vol 157, 111-117, Jan 2009
**Belcaro G, et al. Atherosclerosis 2001; 156: 379-387
The Panasonic Solution: Find a Plaque, Treat It.
We have engineered a product that not only improves your ability to see the underlying disease, but also fits seamlessly into your treatment regimen. Innovative ultrasound imaging technology allows for direct identification of atherosclerotic cardiovascular disease (ASCVD). By combining traditional risk factors with imaging, physicians are able to gather a more comprehensive understanding of their patients’ cardiovascular health.
The CardioHealth Station in the hands of a trained
professional is the perfect in-office tool. Driven by advanced hardware, it automates many of the steps which a sonographer would usually need to understand and perform, making it easy to start using right away and on your own schedule.
Easy to Integrate into Your Practice to Help You Start Making Informed Decisions
Carotid Intima-Media Thickness (CIMT) and Plaque Assessment by Trained Medical Residents: Validation and Preliminary Testing of a Training Protocol.
A recent study published by physicians out of Mayo Clinic and the University of Southern California assessed how easy it was to train medical residents to use ultrasound imaging to identify plaque and measure CIMT. The conclusion was that it was easy to rapidly train medical residents, who had no prior ultrasound training, to identify ASCVD with an accuracy comparable to experts.*
*Aldridge et al., J Am Soc Echocardiogr. Sept 2013. pii:S0894-7317(13)00635-4
Rapid Screening for Subclinical Atherosclerosis by Carotid Ultrasound Examination. The HAPPY (Heart Attack Prevention Program for You) Substudy.
A major study done in India, under the guidance of leading physicians from Mt. Sinai, sought to determine the feasibility of performing ultrasound imaging in a rural young population with few to no risk factors. The results proved that not only was rapid community screening of subclinical atherosclerosis possible, but also useful for identifying the high prevalence of atherosclerotic cardiovascular disease (ASCVD) where traditional risk factors were not available.*
*Singh, Fuster, Narula et al., Global Heart. Vol. 8, No. 2, 83-89, June 2013
The above articles are not shown as an endorsement of the CardioHealth Station, but rather as a highlight of publically available scientific data, which may be referred to by the medical professional.
Find a Plaque, Treat It.
The CardioHealth Station brings efficiency, innovation, and reliability to your medical practice. As a pioneer in its field, it offers improvements in workflow without disrupting your current routine, allowing you to use it on
your own schedule. The tool you always wished you had is finally here to help you make more informed decisions.
A powerful in-office solution allowing you to image patients and find the results in real-time, on your own schedule. Automation and proper training gives you a powerful tool for plaque detection.*
Automation delivered with proprietary technology gives you a reproducible and reliable solution for your practice. Only product in the industry to be FDA cleared for its automated acquisition of IMT measurements of the peripheral vessels.**
Provides real-time arterial plaque imaging allowing you to make more informed decisions while also creating a unique way to increase patient adherence to therapy through proper counseling.
*Aldridge et al., J Am Soc Echocardiogr. 2013 Sep 16. pii:S0894-7317(13)00635-4
**Accurate as of March 2011
In most cases, the entire test takes no longer than five minutes allowing you to create a comprehensive cardiovascular risk assessment very quickly. A detailed report is generated based on traditional risk factor scores (FRAMINGHAM, SCORE or PROCAM) and the results of the ultrasound examination (plaque and IMT) are plotted against your choice of a major study, whether it be ARIC, MESA, or CAPS. Developed in close cooperation with key opinion leaders in preventive cardiology and subclinical atherosclerosis imaging, the report is optimized for you and your patients. The combination of schematic and actual ultrasound images to depict wall thickness and arterial plaque may serve as a clever solution to increasing patient adherence to treatment.
Comprehensive Report Generated with Images
New Treatment Guidelines
Is Testing for Atherosclerotic Disease Recommended?
Yes! Detecting early stage Atherosclerosis by finding focal lesions or an abnormal IMT is more highly recommended by national societies than several other well-known tests.
Class IIA (Strong)
Class IIA (Weak)
Carotid intima-media thickness measurement is a quantitative measurement of atherosclerosis
Key Automatic Features
|(A) Result Of IMT Measurement||Calculated from automation based on the radio frequency data received by the ultrasound probe. Measurement accuracy not dependent on image quality and resolution.|
|(B) Auto Roi||Determines depth of carotid and region of interest to vessel far wall automatically.|
|(C) Auto Trigger||Performs a real-time analysis of the movements of carotid wall from change in vessel diameter and automatically detects cardiac enddiastole when IMT is the thickest.|
|(D) Auto Imt||Determines the intima-media thickness through the collection of raw data and is not dependent on the image resolution.|
|(E) Angle Display||Angle is displayed and recorded along with the IMT measurement.|
|(F) Auto Freeze||Freezes automatically (measurement completed) when reliability of IMT measurement reaches high quality, and trigger occurs.|
CardioHealth Station Technical Specifications
|Display||LCD Monitor with touch panel (Size:15 inch)|
|Weight||13 kg (includes transducer, desk stand, and holder)|
|Modes Of Operation||B Mode / BIMT Mode / CFD / PWD (Realtime / Freeze)|
|Power||100 V to 240 V|
|Ultrasound Image View||• Direction rotates 90ºC or totation (Vertical/Horizontal)|
• Depth 2 cm-5 cm
• Transducer Angle Recording
|Transducer||• Linear array|
• Center frequency (8.9 MHz)
• Cable length (1.5 m)+A1
|Operation Environment (Includes Transducer)||• Ambient temperature: 10ºC to 35ºC|
• Relative humidity: 35% to 80% (no condensation)
|Size||406(W)x131(D)x394(H) Excludes stand and holder|
|Image Paramter Settings||Auto Freeze Condition (Difficult / Normal / Easy)|
|Memory For Imaging||• Multi-angle IMT measurement mode|
• Plaque search mode (B-mode/CFD/PWD)
• Auto IMT measurement
• Modify trace
|Beam Focus||Full digital, transmit focus step 1 (single), dynamic receive focusing|
|Reports||• CardioHealth report|
• DICOM format export
• Network export capability
• Optional USB printer
|Data Storage||• Ultrasound images|
• Patient information
• Angle information
• Measurement information
• Image parameter setting
Read our White Paper, Defy Your Age with Cenegenics®, and learn about the science of age defiance and the Cenegenics® process.
Free advice from Cenegenics® physicians, video testimonials from patients, and other news.
Read regular updates from Cenegenics® on our blog.